Phospho1 gene

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August undefined, 2024

WebMay 10, 2024 · Phospho1 is upregulated during mineralization of vascular smooth muscle cells (VMSCs) in culture, whereas Phospho1 –/– VSMCs exhibited a significant reduction … WebPHOSPHO1 is a recently identified phosphatase expressed at high levels in the chicken growth plate and which may be involved in generating inorganic phosphate for skeletal matrix mineralization [20]. We isolated MVs from growth plate chondrocytes and confirmed the presence of high levels of PHOSPHO1 by immunoblotting [22].

PHOSPHO1 Serves as a Key Metabolism-Related Biomarker in the …

WebApr 11, 2024 · Gene expression analyses. RNA extraction was performed using the RNAeasy Mini Kit (74106, QIAGEN) following the manufacturer’s instructions. ... PHOSPHO1, SLC11A1 and IL-33 . These data suggested that activation of WT KLF1 in the iKLF1-WT macrophages had a greater effect on the transcriptome than the activation of mutant KLF1-E325K. WebPHOSPHO1 cDNA ORF clone, Bos taurus (cattle) Gene Clones gRNAs The following PHOSPHO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PHOSPHO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. css script in head

Phospho1 MGI Mouse Gene Detail - MGI:2447348 - phosphatase, orphan 1

WebOct 22, 2024 · Gene and protein expression of Phospho1 mRNA and PHOSPHO1 protein in murine tissue (a) RT-qPCR of Phospho1 in murine tissues, high expression was seen in … WebComputed orthologs for PHOSPHO1 - phosphoethanolamine/phosphocholine phosphatase 1 WebNational Center for Biotechnology Information css scrollable false

Frontiers The emerging roles of PHOSPHO1 and its regulated ...

WebJun 30, 2024 · Treatment of mice with the PHOSPHO1 substrate phosphocholine is sufficient to induce cold tolerance, thermogenic gene expression, and allied metabolic benefits. Our results reveal a role of PHOSPHO1 as a negative regulator of BAT thermogenesis, and inhibition of PHOSPHO1 or enhancement of phosphocholine … WebOct 22, 2024 · This study identifies PHOSPHO1 as a potential bone-derived therapeutic target for the treatment of obesity and diabetes. We show that mice lacking the bone … css scrollable flexboxWebMar 21, 2024 · PHOSPHO1 (Phosphoethanolamine/Phosphocholine Phosphatase 1) is a Protein Coding gene. Diseases associated with PHOSPHO1 include Periarthritis and Hypophosphatasia, Childhood . Among its related pathways are Glycerophospholipid … ACHE (Acetylcholinesterase (Cartwright Blood Group)) is a Protein Coding gene. … CD200R1 (CD200 Receptor 1) is a Protein Coding gene. Diseases associated with … PGAM1 (Phosphoglycerate Mutase 1) is a Protein Coding gene. Diseases … css script font

"WebPHOSPHO1 is a highly conservative gene with homologs across multiple species. Human-derived, chicken-derived, and mouse-derived PHOSPHO1 genes showed conserved … " - Phospho1 gene

Phospho1 gene

Perspective on Dentoalveolar Manifestations Resulting From …

WebJun 28, 2024 · Among these genes, PHOSPHO1 is the only one directly related to PC metabolism. We thus examined PHOSPHO1 messenger RNA (mRNA) expression by real-time quantitative reverse transcription PCR to confirm the temporal increase of PHOSPHO1 expression during terminal erythropoiesis (Figure 1E ). WebZFIN Gene: phospho1 Gene phospho1 ID ZDB-GENE-040801-198 Name phosphoethanolamine/phosphocholine phosphatase 1 Symbol phospho1 Nomenclature History Previous Names sb:cb839 zgc:92423 ( 1) Type protein_coding_gene Location Chr: 3 Mapping Details/Browsers Description Predicted to have phosphatase activity.

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WebAug 28, 2024 · PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 Gene ID: 162466, updated on 28-Aug-2024 Gene type: protein coding See all available tests in GTR … WebSep 5, 2024 · The cyto-phosphatase PHOSPHO1 generates phosphate from membrane phospholipid C through hydrolyzed phosphocholine and phosphoethanolamine. Type III Na/Pi cotransporter is also given for phosphates both on the cell membrane and on the vesicle matrix membrane.

WebFeb 3, 2024 · Given that the skeletal manifestations of genetic ablation of the Phospho1 gene in mice resemble many of the manifestations of HPP, we propose that Phospho1 … WebMay 1, 2024 · Orphan phosphatase 1 (PHOSPHO1; EC 3.1.3.75; encoded by the Phospho1 gene in the mouse and the PHOSPHO1 gene in humans) has been an increasing focus of research in this

WebMay 5, 2024 · Here we show that mice lacking the bone mineralization enzyme PHOSPHO1 (Phospho1-/-) exhibited improved basal glucose homeostasis and resisted high-fat-diet induced weight gain and diabetes.... WebPHOSPHO1 has 2,767 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 59 datasets.

WebDec 20, 2024 · Phospho1-R74X-null mutant mice (Phospho1 KO) were generated and maintained as previously described. 31 This strain carries a C>T mutation in codon 74 of exon 2 of the Phospho1 gene leading to a premature stop codon (R74X) and the complete absence of PHOSPHO1 protein. 31 All animal experiments were approved by the Roslin …

WebPHOSPHO1 is predominantly expressed in BAT. ( A) Phospho1 mRNA expression from the mouse ENCODE dataset. ( B) Phospho1 mRNA expression in WT-1 brown adipocyte cells … earltownWebJul 26, 2024 · Common variant gene-level associations for PHOSPHO1 as the closest gene with metabolic disorders indicators. Frontiers in Physiology frontiersin.org 04 Liu et al. 10.3389/fphys.2024.935195 earl townes morristown njWebPho1. Pho1 of A. thaliana is a member of the PHO1 family (11 paralogues in A. thaliana).This protein is 782 amino acyl residues in length and possesses 7 … earltown general storeWebZFIN Gene: phospho1 Gene phospho1 ID ZDB-GENE-040801-198 Name phosphoethanolamine/phosphocholine phosphatase 1 Symbol phospho1 Nomenclature … css scrollable table bodyWebWe found that phosphatase, orphan 1 (PHOSPHO1) is positively regulated by regulatory factor X5 (RFX5) and mediates MYC proto-oncogene (MYC) targeting the V2 pathway and … css scrollableWebWe found that phosphatase, orphan 1 (PHOSPHO1) is positively regulated by regulatory factor X5 (RFX5) and mediates MYC proto-oncogene (MYC) targeting the V2 pathway and neutrophils. Keywords: PHOSPHO1; diffuse large B-cell lymphoma; immune microenvironment; metabolism-related gene; regulatory network. © 2024. earltown rootsWebDec 1, 2003 · PHOSPHO1 gene expression has also been detected in the human mineralizing osteoblast‐like cell line, SaOS‐2 (but not in the MG‐63 non‐mineralizing osteoblast‐like cell line) and immunohistochemical staining with anti‐PHOSPHO1 antibody has shown the protein to be present at mineralizing regions in chick bone (Houston et al., … css scrollable table