Poly rc binding protein 4

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August undefined, 2024

WebNov 4, 2024 · PCBP2 post-transcriptionally regulates sortilin expression by binding to a C-rich element in its 3' UTR. Embryos lacking the KH domain poly (C) binding protein, Pcbp2, are selectively deficient in the definitive erythroid lineage. Compared to wild-type controls, transcript splicing analysis of the Pcbp2 (-/-) embryonic liver reveals accentuated ... WebNov 1, 2024 · Iron chaperones include the multi-functional poly(rC)-binding proteins 1–4 (PCBPs). • PCBP1/2 play roles in iron metabolism, with the roles of PCBP3/4 being less clear. • The PCBPs bind 3 iron atoms and form hetero/homo dimer complexes. • PCBPs have a subset of non-redundant functions in iron metabolism.

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WebSep 10, 2009 · Leffers et al. (1995) described the cloning and characterization of 2 cDNAs for poly(rC)-binding proteins, called PCBP1 and PCBP2 (601210) by them. The authors analyzed an EST database for sequences that were predicted to encode a protein with K-homologous (KH) domains. WebPCBP1. Poly (rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene. [5] This intronless gene is thought to have been generated by retrotransposition of a … smart angel interlocking play mat

Poly a binding protein Sigma-Aldrich

WebPoly(rC)-binding protein 4 is a protein that in humans is encoded by the PCBP4 gene.. This gene encodes a member of the KH domain protein subfamily. Proteins of this subfamily, … WebRationale: Proper development of the heart relies on a tightly regulated, yet diverse, pattern of gene expression that is governed by transcriptional, post-transcriptional, and translational processe WebSingle-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:7607214, PubMed:12414943). Major cellular poly(rC)-binding protein … smart animal husbandry care

59092 - Gene ResultPcbp4 poly(rC) binding protein 4 [ (house …

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WebApr 1, 2024 · Download Citation On Apr 1, 2024, Oliveira AG and others published Interaction between poly-A binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response ... WebDec 8, 2024 · Orthologous to human PCBP4 (poly(rC) binding protein 4). [provided by Alliance of Genome Resources, Apr 2024] Other designations. poly(rC)-binding protein 4, alpha-CP4. GeneRIFs: Gene References Into Functions. the p53-PCBP4-ZFP871 axis represents a novel feedback loop in the p53 pathway. ... hill country custom towingWebFeb 28, 2024 · The cellular RNA-binding protein poly(rC)-18 binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5´ 19 untranslated region (UTR), but its importance in the viral life cycle has remained unclear. 20 Herein, we aimed to clarify the role of PCBP1 in the HCV life cycle. smart angelical red download

"WebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with … " - Poly rc binding protein 4

Poly rc binding protein 4

WebPoly(rC)-binding protein 4 is a protein that in humans is encoded by the PCBP4 gene.. This gene encodes a member of the KH domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular … WebJan 19, 2011 · Leffers et al. (1995) described the cloning and characterization of 2 cDNAs for poly (rC)-binding proteins, called PCBP1 ( 601209) and PCBP2 by them. The authors analyzed an EST database for sequences that were predicted to encode a protein with K-homologous (KH) domains. The 60- to 70-amino acid KH motifs are found in several …

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WebSynonym(s): Anti-Poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations SDS; AV40943: polyclonal: WB: rabbit, human: 1: Expand. … WebJul 1, 2024 · Poly(rC)-binding protein 2 (PCBP2) is a member of the poly-cytosine binding protein (PCBP) family, which has been shown to function as regulators in various diseases, including hepatitis C virus infection [2], degenerating neurons [3], acute spinal cord injury [4], and chronic obstructive pulmonary disease [5].

WebMar 21, 2016 · PCBP4 (Poly(RC) Binding Protein 4) is a Protein Coding gene. Diseases associated with PCBP4 include Maxillary Cancer and Jaw Cancer.Among its related … WebPCBP2 knockdown promotes ferroptosis in malignant mesothelioma. PCBP2 might play important roles in central nervous system pathophysiology after spinal cord injury. that the change of poly (C)-binding proteins protein expression was associated with Schwann cell proliferation after the trauma of the peripheral nervous system.

WebOct 15, 2024 · Poly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a relative molecular weight of 38 kDa, which is characterized by downregulation in many cancer types. Numerous cases have indicated that PCBP1 could be considered as a tumor suppressor to inhibit tumorigenesis, development, and metastasis. WebFind poly a binding protein and related products for scientific research at MilliporeSigma. US EN. Applications Products ... Synonym(s): Anti-LIP4, Anti-LYST-interacting protein, Anti-MCG10, Anti-RNA binding protein MCG10, Anti-poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations SDS; SAB2500758 ...

WebJul 21, 2015 · In the present study, we specifically examined Poly(rC)-Binding Protein 4 (PCBP4), which reportedly induces G2/M arrest. Results showed that suppression of …

WebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with … smart angle cube hill country deer hunting podcastWebPoly(rC)-Binding Protein 4 (PCBP4) is an RNA-binding protein (RBP). It plays an important role in stabilizing mRNA and translation7,8. The PCBP family consists of hnRNP K, PCBP1, … smart android watches for menWebFeb 26, 2024 · Small hairpin RNA-mediated depletion of PCBP2 dramatically decreased the viability of gastric cancer cells. Cyclin-dependent kinase 2 (CDK2) was positively regulated by PCBP2 via a direct 3′ UTR binding pathway as determined using a ribonucleoprotein immunoprecipitation assay and a biotin pulldown assay. CDK2 mediated the promoting … smart animal rescue batlowWebGene ID: 128047921, updated on 28-Feb-2024. Summary Other designations. poly(rC)-binding protein 2 smart animal husbandryWebinternal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein … smart animal sanctuaryWebJul 4, 2024 · Previous studies have shown that poly (rC) binding protein 2 (PCBP2) belonging to a class of proteins that bind to poly (C) stretches of both RNA and DNA, recruits HECT-domain–containing E3 ... hill country custom cycle